Stasinos Chr. Sikalias · The science of compounding

Batch worksheet: Aprepitant 20 mg/mL from 80 mg capsules — source discrepancy

CGR-FR-030 · Blank fields for controlled execution

Use on holdCGR-FR-030France

DO NOT COMPOUND — unresolved source inconsistency.

COMPOUNDING ON HOLD: an unresolved critical discrepancy exists. This record is for study and investigation; do not execute until a documented resolution is available.

Aprepitant: monograph uses 4 × 80 mg; the 80 mg technical note (18/05/2026, p.2) method says 4 × 125 mg. Do not compound pending publisher clarification. The 16 mL is added vehicle, not q.s. ad.

Aprepitant: monograph uses 4 × 80 mg; the 80 mg technical note (18/05/2026, p.2) method says 4 × 125 mg. Do not compound pending publisher clarification. The 16 mL is added vehicle, not q.s. ad.

Companion batch worksheet. Use with the full monograph and a locally approved master record. This is not a standalone recipe. Complete by hand after printing.

Full monograph PDF

CGR-FR-030 · Monograph 4.0 · Web 4.0 · 10.09.2026

Local master ID / versionBatch / date

Materials and actual quantities

MaterialSourceLocal targetActual amountLot / expiry / check
Aprepitant 80 mg capsules4 καψάκια / capsules
Ora-Blend OR Ora-Blend SF16 mL ΠΡΟΣΘΗΚΗ / ADDED

Local batch size, units, calculations and independent check

Line clearance, equipment, calibration and cleaning

Stages, times, actual parameters and observations

Yield, losses and reconciliation

QC: samples, methods, limits and actual results

Deviations, investigation and decision

Packaging, label, storage and actual BUD justification

Operator, reviewer and releasing pharmacist — signatures / dates